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Our services
CHO and HEK stable
cell line development
Host system CHOExpress®, outstanding technologies for fast generation of high-yield cell lines, and scalable manufacturing processes are the result of more than 20 years of deeply committed research, innovation, and optimisation.
Any Protein Format
mAbs, bispecifics, fusion proteins,
biosimilars, virus suface proteins, etc.
Speedy timeline
From DNA to stable, high-yield clone in 8 weeks
Robust cells for scalable processes
Scalability to over 5’000 L without loss of productivity
High Titers
Up to 14 g/L, fully chemically defined process
Unmatched Clone Stability
Over 95% of our clones are stable
From DNA to IND
Your gene is integrated into transcriptionally active DNA, guaranteeing high productivity, high cell line stability (>95%), and high comparability between stable pools and clonally derived cell lines.
- Extensive media and feed screening to identify optimal production conditions
- Cell line stability study is included
- Development of scalable upstream and downstream processes and tech transfer (optional)
- Use of Design of Experiments (DoE) for process optimization
- State-of-the-art FDA and EMA compliant cloning procedures for documented proof of clonality
- Support for assay development and analytics
- Cell line development reports that support clinical trials and market authorization (IND, CTA/BLA, MAA)
- Full freedom in the choice of media and feeds, including proprietary media
- Licensing opportunities for the CLD platform are available.
Request a free quote for your project today.
From DNA to product: do it right, from the start.