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Cell line development services

ExcellGene’s exceptional host system CHOExpress®, outstanding technologies for fast generation of high-yield cell lines, and scalable manufacturing processes are the result of more than 20 years of deeply committed research, innovation, and optimisation.


High Titers

Up to 14 g/L, fully chemically defined process


Speedy timelines

From DNA to stable,
high-yield clone in 8 weeks


Diverse protein formats

mAbs, bispecifics, fusion proteins, biosimilars, virus surface proteins



Robust cells for scalable processes

100 L, 500 L, 2000 L, 10’000 L

What properties make CHOExpress® host cells exceptional?

Fast growing

19 hours doubling time

Growth to high density

>35 Mio cells/mL in fed-batch culture

High sub-cultivation ratios

Higher than 1:20

cGMP compliant


Developing your cell line with ExcellGene

Each project is customized for the clients’ needs and handled by a dedicated team

Benefit from more than 20 years of expertise in cell line development and manufacturing technology.

We are deeply committed to achieve your milestones, timelines and target titers.

Your cell line development timeline

From DNA to IND

Your gene is integrated into transcriptionally active DNA, which guarantees high productivity, high cell line stability (>95%) and high comparability between stable pools and clonally derived cell lines.

  • Extensive media and feed screening to identify optimal production conditions
  • Cell line stability study is included
  • Development of scalable upstream and downstream processes and tech transfer (optional)
  • Use of Design of Experiments (DoE) for process optimization
  • State-of-the-art FDA and EMA compliant cloning procedures for documented proof of clonality
  • Support for assay development and analytics
  • Cell line development reports which support clinical trials and market authorization (IND, CTA/BLA, MAA)
  • Full freedom in choice of media and feeds, including proprietary media
  • Licensing opportunities for the CLD platform are available.

Download the PDF

For your convenience, this overview of our cell line development services is available as a downloadable PDF.