Expect great science.
It’s in our DNA.
ExcellGene’s reliable process and exceptional CHO cell hosts are the result of over twenty years of innovation and fine-tuning.
Since 2001, ExcellGene has developed proprietary technologies and know-how that are key for the delivery of its clients’ projects on a timely manner and with a high degree of customization.
CHO and HEK stable cell line development
High Throughput Protein Production
cGMP Cell Bank Manufacturing
Out licensing of
superior cell hosts
In-house state-of-the-art tech
revolutionizing your development programs.
The fastest growing CHO host for biotech
We developed a uniquely high-performing production host system for large-scale manufacturing. CHOExpress® derivative clonal populations commonly show fast growth to densities over 20 million cells/mL, process yields over 5 g/L, and great robustness for high-scale manufacturing (1oo doublings).
The cell line is the result of nearly a decade of work, and is validated with FDA and EMEA cell line documentation, including TSE, BSE and mycoplasma-free statements. The cell line is immortalized.
CHOExpress® is highly compatible with other systems, and can be used royalty-free. ExcellGene will guide you in ensuring favorable phenotypes in CHOExpress®-derived clonal populations. Our knowledge on gene transfer and isolation of top-performing cell populations is at your disposal.
A high performance chemically defined medium formulation for growth and production and for biosimilar quality adjustements.
Pioneering single-cell suspension for transient gene expression and virus like particle production
HEKExpress® is a fast-growing, productive and robust HEK-293 derived cell line for large-scale manufacturing of recombinant proteins.
After nearly a decade of work with the adherent cell line, ExcellGene has generated an aggregate-free single-cell suspension culture with very high transfection efficiency. This also means scale-up in serum-free, animal component-free or chemically defined media is easy.
HEKExpress® demonstrates the highest TGE yield ever reported in the literature (> 1g/L). HEK-293 cells are commonly used for academic research, and are very suited for transient gene expression. The host system can be licensed along with our proprietary chemically defined medium.
- A single-cell suspension host system for TGE and VLP production
- Highest transient expression yield ever reported in the literature (> 1g/L)
- Highly efficient in AAV9 production and lentivirus. Baculovirus-free
- Fully characterized, ready for cGMP master cell bank generation and cGMP production
- Single-cell suspension – no aggregates!
- Easy scale-up in various animal component free media types
- High cell density culture in ExcellGene’s CD media and feeds.
HEKzeroT® host cells
A clonally derived, T-antigen-free host cell system with superior AAV-VLP production capacity.
A high performance chemically defined medium formulation for growth and production for recombinant proteins.
Dynamic Portfolio of
Cost and time-savings, while bringing your product to the market.
Choose from our range of high-producing clonal Research Cell Banks (RCBs), providing the option to seamlessly integrate affiliated Upstream (USP) and Downstream (DSP) processes and respective analytics, all available for immediate transfer.
Tailored On-Demand Biosimilar Services :
Adapted to your specific needs, we deliver high-producing biosimilar clones developed from DNA to research cell bankswithin 2 months. Benefit from our complete USP, DSP and analytical capabilities, along with characterized Master Cell Banks (MCB), provided in less than a year.
Furthermore, we offer biosimilarity optimisation for your existing cell line, customized to your targeted market.