OUR OFFERINGS

Expect great science.
It’s in our DNA.

ExcellGene’s reliable process and exceptional CHO cell hosts are the result of over twenty years of innovation and fine-tuning.

OUR SERVICES

A uniquely
science-driven CDMO

Since 2001, ExcellGene has developed proprietary technologies and know-how that are key for the delivery of its clients’ projects on a timely manner and with a high degree of customization.

CHO and HEK stable cell line development

Bioprocess Development

High Throughput Protein Production

Tox Material

cGMP Cell Bank Manufacturing

OUR TECHNOLOGIES

Out-licensing of
superior cell hosts

In-house state-of-the-art tech
revolutionizing your development programs.

CHOExpress®
cell hosts

The fastest growing CHO host for biotech

We developed a uniquely high-performing  production host system for large-scale manufacturing. CHOExpress® derivative clonal populations commonly show fast growth to densities over 20 million cells/mL, process yields over 5 g/L, and great robustness for high-scale manufacturing (1oo doublings).

The cell line is the result of nearly a decade of work, and is validated with FDA and EMEA cell line documentation, including TSE, BSE and mycoplasma-free statements. The cell line is immortalized.

CHOExpress® is highly compatible with other systems, and can be used royalty-free. ExcellGene will guide you in ensuring favorable phenotypes in CHOExpress®-derived clonal populations. Our knowledge on gene transfer and isolation of top-performing cell populations is at your disposal.

CHOExpress®

A robust, scalable and highly
productive cell host.

FlexiCHO® medium.

A high performance chemically defined medium formulation for growth and production and for biosimilar quality adjustements.

HEKExpress®
cell hosts

Pioneering single-cell suspension for transient gene expression and virus like particle production

HEKExpress® is a fast-growing, productive and robust HEK-293 derived cell line for large-scale manufacturing of recombinant proteins.

After nearly a decade of work with the adherent cell line, ExcellGene has generated an aggregate-free single-cell suspension culture with very high transfection efficiency. This also means scale-up in serum-free, animal component-free or chemically defined media is easy.

HEKExpress® demonstrates the highest TGE yield ever reported in the literature (> 1g/L). HEK-293 cells are commonly used for academic research, and are very suited for transient gene expression. The host system can be licensed along with our proprietary chemically defined medium.

Features

  • A single-cell suspension host system for TGE and VLP production
  • Highest transient expression yield ever reported in the literature (> 1g/L)
  • Highly efficient in AAV9 production and lentivirus. Baculovirus-free
  • Fully characterized, ready for cGMP master cell bank generation and cGMP production
  • Single-cell suspension – no aggregates!
  • Easy scale-up in various animal component free media types
  • High cell density culture in ExcellGene’s CD media and feeds.

HEKzeroT® & HEK2Express®

Clonally derived, T-antigen-free host cell systems with superior AAV-VLP production capacity.

FlexiHEK® medium.

A high performance chemically defined medium formulation for growth and production for recombinant proteins.

Request a free quote for your project today.

From DNA to product: do it right, from the start.