HEK 293 Cell Line Development
Optimizing titers for complex proteins and difficult-to-express proteins with HEKExpress®
cell line.
OUR HEKExpress®
In fast developing biotech, we are experiencing a pickup in more complex protein designs and need for specific protein quality attributes. Our HEK2Express® cell line often yields better results.
Benefits of using ExcellGene’s HEKExpress®
Flexibility
The ExcellGene’s HEK 293 CLD platform is flexible and robust.
Clonable Cells
HEKExpress® cells are easily to clone and to maintain in single-cell suspension.
Stability
HEKExpress®-derived clones remain stable for prolonged period culture (≥ 3 months), maintaining genetic and phenotypic profile.
Timelines
The HEK 293 platform follows similar development timelines comparable to the CHO platform.
Scalability
HEK 293 platform processes are scalable, running different processes at various scales of stirred tank reactors (STRs).
Protein Quality
Specific genetic makeup of HEK 293 cells can often deliver desired protein quality without compromising volumetric productivity.
Intracellular mechanisms
Biological difference of HEK 293 cells, can allow for expression of proteins perceived hard-to-express, complex or toxic for CHO host.